Systemic Lupus Erythematosus Treatment Market Opportunity Analysis 2018-2026

Systemic Lupus Erythematosus (SLE) is chronic autoimmune disorder. It is characterized by excess production of the antibodies that attacks body’s own cells and vital organs. Various symptoms associated with the disease includes joint pain, swelling, rashes over face (butterfly rash) and other body area, severe fatigue, hair loss, anemia, and Raynaud’s phenomenon etc. SLE can also affect vital body organs such as heart, kidney, lungs, and behavioral changes. Exact causes of the disease is unknown, however, hereditary and environmental factors could be lead to SLE.

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There is no direct cure available for SLE, however, symptomatic treatment can be administered to lower or eliminate symptoms associated with disease. Major classes of drugs commonly used are antimalarial agents such as chlorquine and hydrochlorquine; topical steroid cream for rashes; NSAIDS for joint pain; and fever steroidal medication such as glucocorticoids through IV or oral route and immunosuppressive agents to lower immune response from the antibodies.

Rise in incidence of SLE is one of major factors driving growth of the systemic lupus erythematosus treatment market. According to study published in the Expert Review of Clinical Immunology in 2017, the global incidence rate varied from about 0.3–23.7 per 100,000 person and the prevalence rates varied in the range from 6.5 to 178.0 per 100,000 people. Key companies are entering into collaborations for research and development in systemic lupus erythematosus, which is expected to support growth of the market.

For instance, in 2015, a genomic mapping company, 23andMe, Inc. collaborated with Pfizer, Inc. to study and understand the genetics of lupus thereby, to develop treatment for it. In 2012, Alliance for Lupus Research and Pfizer’s Centers for Therapeutic Innovation collaborated to discover new therapies for patients living with systemic lupus erythematosus. Increasing approvals for products for the treatment of SLE is another factor expected to aid in growth of the market. For instance, GlaxoSmithKline, in July 2017, received U.S.FDA approval for the subcutaneous form of its biologic drug belimumab for treatment of systemic lupus erythematosus. Clinical guidelines to include biologics in the treatment of systemic lupus erythematosus would further aid in market growth.

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Key Vendors:

GlaxoSmithKline Plc (GSK), F. Hoffmann-La Roche Ltd, Anthera Pharmaceuticals Inc., Bristol-Myers Squibb, Eli Lilly, Pfizer Limited, Merck KGaA, Immupharma Plc, Sanofi, Lycera Corporation, Aurinia Pharmaceuticals Inc., Mylan N.V., and Sandoz International GmbH.

Gulmarg Holiday Packages And Popular Tourist Places

Gulmarg is a hill station situated in the state of Jammu and Kashmir of India. Its literal meaning is ‘meadow of flowers’ or the place of roses and is a popular skiing spot in the district of Baramula. The place is located at 52 kilometers from Srinagar well within the range of the Himalayas and is only a few miles from the international border between India and Pakistan having an average elevation of 8825 feet. The temperature ranges between as low as 4 degrees to 6.3 degrees and the average rainfall is around 25.86 inches. The tourists can enjoy the weather during the summer season when there is scorching heat elsewhere on the plains.

The place located under the imposing hills of the Himalayas is a fascinating place for the tourists. One can reach Gulmarg easily from Srinagar, the state capital, or from the Srinagar airport within two hours by road. Another place called Tanmarg is about an hour’s journey from Srinagar on way to Gulmarg. Tanmarg is also a main tourist attraction and main destination for the skiers skiing down from Gulmarg during the winter season. Gulmarg is just thirty minutes journey from Tanmarg and has several accommodations available at a budget ranging as low as Rs.500/ per night in a hut to as high as Rs6500/ per night with five star facilities. The ropeway Gulmarg Gondola, a cable car operating at such a high altitude is considered as one of the highest in the world. Some other tourist destinations in the vicinity of Gulmarg are Baba Reshi, Tanmarg and Haji Murad at Kreeri that all are places of religious importance and situated within a radius of around 20 kilometers. It is the heartland of winter sports in India.

During the winter, the terrains combine with diverse climatic conditions, such as torrential rains and snowfalls, to make the place a paradise for adventure and nature loving persons from all over the world.

Gulmarg is well connected by road and air. Several tour operators provide the facilities of luxury cars and air-conditioned buses from most of the cities of north India including Amritsar, Ludhiana, Delhi, Agra, Kanpur, and Jaipur to name a few. One can go up to Srinagar by air. They offer a number of holiday packages which include staying, sightseeing and dietary facilities. Their packages are generally for per couple or per person and they make all out efforts to make the tourists stay as comfortable and memorable as possible.

Cold Therapy Unit – an Overview

A cold therapy unit is a machine designed to efficiently deliver cold therapy. It offers a much better alternative to traditional ice packs used for cold therapy.Cold therapy is the use of freezing temperatures to heal orthopedic injuries and pain. The cold temperature temporarily blocks blood supply on the application site by hindering nerve communication in the same area. Without a blood supply, the inflammation and the pain begin to reduce.Cold therapy works best when used consistently and via the right delivery methods. Rudimentary ice packs are really not ideal for the task. It is best to use a cold therapy unit for delivering cold therapy.The DesignCold therapy units consist of several components such as a pump, a tank, a healing pad, a connecting tube, and an adapter. These components work seamlessly to deliver cold temperature over wounds or injuries.The healing pad covers the injured area. The tank stores the water and ice. The pump aids the flow of water from the tank to the healing pad via the tube.Brands like IsoComforter use the patented Iso tube technology to design their cold therapy units. The use of this advanced technology helps to build machines that can deliver cold therapy safely and optimally. IsoComforter also ensures that its cold therapy units are easy to use. The use of self-priming pumps and easy mechanisms make it very easy to use IsoComforter machines.IsoComforter machines also have healing pads with ridge design to ensure optimal contact of the skin with the cold temperature. The ridges help to prevent burn injuries on the skin due to excessive freezing temperatures.UsesYou can use a cold therapy unit to heal orthopedic injuries of all kinds. Be it fractures, ligament tears, or ruptured tissues; you can use a cold therapy unit for consistent and efficient delivery of cold therapy.It is also helpful for speedy healing of patients post their back, knee, shoulder, and hip surgeries. Cold therapy helps patients regain range of motions in their joints sooner than expected post knee or shoulder injuries by experiencing reduced pain in a speedy manner. It helps them to begin their physical therapy without any delay.You can also use a cold therapy unit to treat sore and fatigued muscles.BenefitsA cold therapy unit helps users deliver cold therapy in a safe manner. For post-surgical healing, patients need a way to administer cold therapy easily, safely, consistent, and conveniently.Unlike ice packs, a cold therapy unit doesn’t drip water over incisions or open wounds.It is also easy to use a cold therapy unit. You can actually sit back and relax while the machine does its job. When you use IsoComforter machines, you won’t need to replenish ice in the tank very often. Ease of use of the machines enables the patients to administer cold therapy consistently. You can then experience speedy healing with natural therapy without resorting to pain medicines.